Pufferfish Meditate Magnesium

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Scientists at Tokyo Institute of Technology collaborate colleagues at Japan's Shimonoseki Academy of Marine Science and Mayo Clinic College of Medicine, Minnasota, USA, to uncovered the molecular mechanisms behind Mg2+ secretion in fresh and seawater Takifugu pufferfish species.
The bodily functions of creatures that live in aquatic environments are affected by the presence of ions of different elements in the water. Bodies naturally absorb and retain ions as essential nutrients, but an excess of any one ion in the body can be damaging.
The magnesium ion Mg2+ is the second most abundant cation in seawater. Both freshwater and seawater fish maintain a certain level of Mg2+ in the plasma in their bodies, and it has long been known that seawater fish secrete Mg2+ into their urine in order to avoid an excess of absorbed Mg2+ from their surroundings. However, certain species of fish are capable of living in both salt and freshwater conditions, and how they alter Mg2+ secretion in their bodies accordingly is not well understood.
Now, Akira Kato and co-workers at Tokyo Institute of Technology, together with researchers from Japan's Shimonoseki Academy of Marine Science and Mayo Clinic College of Medicine, Minnasota, USA, have uncovered the molecular mechanisms behind Mg2+ secretion in fresh and seawater Takifugu pufferfish species.
"For freshwater fish, Mg2+ is an important nutrient which should be retained if excess Mg2+ is not absorbed from food," explains Kato. "Seawater contains around 30 times more Mg2+ than the blood of seawater fish. If seawater fish cannot excrete excess Mg2+, they face hypermagnesemia which causes failure of normal tissue functions in the nerves, muscles, and heart."